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(RS) -MCPG

CAT: 0804-HY-100371-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-100371-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(RS) -MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS) -MCPG blocks theta-burst stimulation (TBS) -induced shifts in both juvenile and neonatal rat hippocampal neurons[1][2].
CAS Number
146669-29-6
Product Name Alternative
Alpha-MCPG
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/_RS_-MCPG.html
Purity
99.05
Solubility
1M NaOH : 100 mg/mL (ultrasonic; adjust pH to 10 with NaOH) |DMSO : 6 mg/mL (ultrasonic; warming) |H2O : < 0.1 mg/mL (ultrasonic; heat to 80°C)
Smiles
CC(C(O)=O)(N)C1=CC=C(C(O)=O)C=C1
Molecular Formula
C10H11NO4
Molecular Weight
209.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Yang B et al. Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons. PLoS One, 2015 Sep 21, 10 (9) :e0138215.|[2]Fiona Yeuk-Lun Choi, et al. The effects of (RS) -MCPG on amphetamine-induced sensitization in neonatal rats.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR

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