MCPG (sodium)

• Description:

  MCPG is a carboxylic phenyl glycine. MCPG can block metabotropic glutamate receptor (mGluR) (HY-15129) and has antagonistic activity of mGluR subtype. MCPG can be used to study the induction and maintenance of long-term potentiation (LTP) [1].

• UNSPSC:

  12352005

• Target:

  MGluR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/mcpg-sodium.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O[Na])C(C)(N)C1=CC=C(C(O)=O)C=C1

• Molecular Formula:

  C10H10NNaO4

• Molecular Weight:

  231.18

• References & Citations:

  [1]Riedel G, et al. Inhibition of long-term potentiation in the dentate gyrus of freely moving rats by the metabotropic glutamate receptor antagonist MCPG. J Neurosci. 1995 Jan;15 (1 Pt 1) :87-98.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1303994-09-3]