Products for Research Use Only
RegisterLogin

Disopyramide (phosphate)

CAT: 0804-HY-12533A-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-12533A-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Disopyramide phosphate is a class IA antiarrhythmic agent with efficacy in ventricular and atrial arrhythmias. Disopyramide phosphate blocks the fast inward sodium current of cardiac muscle and prolongs the duration of cardiac action potentials. Disopyramide phosphate inhibits HERG encoded potassium channels. Disopyramide phosphate also exhibits complex protein binding, and has a potent negative inotropic action[1][2][3].
CAS Number
22059-60-5
Product Name Alternative
Dicorantil (phosphate) ; SC-7031 (phosphate)
UNSPSC
12352005
Hazard Statement
H302
Target
Potassium Channel; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/disopyramide-phosphate.html
Purity
99.85
Solubility
DMSO : 5.83 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=P(O)(O)O.NC(C(C1=CC=CC=C1)(C2=CC=CC=N2)CCN(C(C)C)C(C)C)=O
Molecular Formula
C21H32N3O5P
Molecular Weight
437.47
Precautions
H302
References & Citations
[1]S V Jones, et al. Non-competitive Effects of Disopyramide at the Neuromuscular Junction: Evidence for Endplate Ion Channel Block. Br J Anaesth. 1987 Jun;59 (6) :776-83.|[2]L A Siddoway, et al. Clinical Pharmacokinetics of Disopyramide. Clin Pharmacokinet. May-Jun 1986;11 (3) :214-22.|[3]A A Paul, et al. Inhibition of HERG Potassium Channel Current by the Class 1a Antiarrhythmic Agent Disopyramide. Biochem Biophys Res Commun. 2001 Feb 9;280 (5) :1243-50.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched

Related Products

CatalogName
HY-12533-01Disopyramide
HY-12533RDisopyramide (Standard)
HY-12533BDisopyramide (hydrochloride)
HY-12119A-01GW274150 (phosphate)
HY-13630-01Etoposide phosphate
HY-B1896A-01Piperaquine (phosphate)
HY-100490B-01Rilmenidine (phosphate)
HY-B0141BPolyestradiol (phosphate)
HY-B1064-01Clindamycin phosphate
HY-135317FEmavusertib (phosphate)

Alternative Products

CatalogName
GTR19201721-01Disopyramide phosphate
sc-252757Disopyramide phosphate salt
272867-01Disopyramide

Popular Products