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CD131 Recombinant Protein

CAT: 0384-NCP0259-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0384-NCP0259-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The common beta-chain (beta-c) of the granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3) and IL-5 receptors is the major signaling subunit of these receptors, coupling ligand binding to multiple biological activities. Tyrosine phosphorylation of cytokine receptor common beta-chain is one of the first events in GM-CSF, IL-3 and IL-5 receptor activation and in signaling initiation. Serine phosphorylation within the 14-3-3 binding sequence of the common beta-chain is also involved in GM-CSF, IL-3 and IL-5 receptor-specific functions.
CAS Number
9000-83-3
Swiss Prot
P32927
Modification Site
NdeI-XhoI
Expression System
Pet-22b (+)
Tag
His-tag
Purity
Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE) .
Solubility
PBS, 4M Urea, PH7.4
Molecular Weight
~47kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Host or Source
E.coli
AA Sequence
TGGGAACGTAGTCTGGCAGGTGCCGAAGAAACCATTCCGCTGCAGACCCTGCGCTGTTATAATGATTATACCAGTCATATTACCTGCCGCTGGGCAGATACCCAGGATGCCCAGCGTCTGGTTAATGTTACCCTGATTCGCCGTGTGAATGAAGATCTGCTGGAACCGGTGAGTTGCGATCTGAGCGATGATATGCCGTGGAGCGCCTGTCCGCATCCGCGTTGTGTGCCGCGCCGTTGCGTTATTCCGTGCCAGAGCTTCGTTGTTACCGATGTTGATTACTTCAGCTTCCAGCCGGATCGTCCGCTGGGTACCCGTCTGACCGTGACCCTGACCCAGCATGTGCAGCCGCCGGAACCGCGTGATCTGCAGATTAGTACCGATCAGGATCACTTCCTGCTGACCTGGAGTGTGGCACTGGGCAGCCCGCAGAGCCATTGGCTGAGTCCGGGCGATCTGGAATTCGAAGTGGTGTATAAACGTCTGCAGGATAGTTGGGAAGATGCAGCCATTCTGCTGAGTAATACCAGCCAGGCAACCCTGGGCCCGGAACATCTGATGCCGAGCAGTACCTATGTTGCCCGTGTTCGTACCCGCCTGGCCCCGGGTAGCCGTCTTAGCGGTCGCCCTAGTAAATGGAGCCCGGAAGTGTGTTGGGATAGTCAGCCGGGCGATGAAGCACAGCCGCAGAATCTGGAATGCTTCTTCGATGGCGCAGCCGTGCTGAGCTGTAGCTGGGAAGTGCGTAAAGAAGTGGCCAGCAGTGTTAGCTTCGGCCTGTTCTATAAACCGAGTCCGGATGCCGGTGAAGAAGAATGCAGCCCGGTGCTGCGCGAAGGTCTGGGTAGTCTGCATACCCGTCATCATTGCCAGATTCCGGTTCCGGATCCGGCCACCCATGGTCAGTATATTGTGAGTGTTCAGCCGCGCCGCGCCGAAAAACATATTAAAAGTAGTGTGAATATCCAGATGGCACCGCCGAGCCTGAATGTGACCAAAGATGGTGATAGTTATAGCCTGCGTTGGGAAACCATGAAAATGCGCTATGAACATATTGATCATACCTTCGAAATCCAGTATCGCAAAGATACCGCAACCTGGAAAGATAGCAAAACCGAAACCTTACAGAATGCACATAGTATGGCCCTGCCGGCCCTGGAACCGAGTACCCGTTATTGGGCCCGCGTTCGCGTGCGTACCAGCCGTACCGGTTATAATGGTATCTGGAGCGAATGGAGTGAAGCCCGCAGTTGGGATACCGAAAGCGTTCTGCCGATGTGG

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