RecombinantCNTF, Rat

CAT: 0384-BK0019-01Size: 10 µgDry Ice: NoHazardous: No
CAT#:0384-BK0019-01Size:10 µg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ciliary Neurotrophic Factor (CNTF) is a polypeptide hormone which acts within the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. CNTF is a potent survival factor for neurons and oligodendrocytes and may play a role in reducing tissue damage during increased inflammation. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, however this phenotype is not causally related to neurologic disease.Recombinant Rat Ciliary Neurotrophic Factor (CNTF) produced in E .coli is a single, non-glycosylated polypeptide chain of 199 amino acids and a molecular mass of 22.9 kDa. It has been purified by chromatographic techniques.
CAS Number
9000-83-3
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% as analyzed by SDS-PAGE.
Bioactivity
ED50 < 30ng/ml, measured by its ability to induce alkaline phosphatase production byTF-1 Cells.
Reconstitution
Reconstituted in ddH2O at 100 μg/ml.
Molecular Weight
22.9 kDa, observed by reducing SDS-PAGE
Storage Conditions
Lyophilized recombinant Rat CNTF remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rrCNTF should be stable up to 1 week at 4°C or up to 3 months at -20°C.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized after extensive dialysis against 50mM Tris, pH 8.0.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.
AA Sequence
AFAEQTPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNINLD SVDGVPVAS T DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LMLQVSAFA Y QLEELMVLLE QKIPENEADG MPATVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVIS S HQMGISALES HYGAKDKQM

Related Products

CatalogName
BK0018-01RecombinantCNTF, Mouse
BK0017-01RecombinantCNTF, Human
BK0300-01RecombinantCNTF, Human (HEK293-expressed)
BK0349-01RecombinantTNF-α, Rat
BK0168-01RecombinantTNF-α, Bovine
BK0171-01RecombinantTNF-α, Human
BK0173-01RecombinantTNF-α, RhesusMacaque
BK0301-01RecombinantCT‑1, Mouse
BK0170RecombinantTNF-α, His, Mouse
BK0145-01RecombinantNT-4, Mouse

Alternative Products

CatalogName
BK0018RecombinantCNTF,Mouse
BK0019RecombinantCNTF,Rat
BK0017RecombinantCNTF,Human
BK0300RecombinantCNTF,Human(HEK293-expressed)

Popular Products