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Anti-SAP97 Antibody

CAT: 1303-75-030Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-030Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Synapse-associated protein 97, Discs Large MAGUK Scaffold Protein 1 or SAP97 is encoded by the gene DLG1. SAP97 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. It is a multi-domain scaffolding protein which serves to recruit receptors channels and other signaling molecules to the plasma membrane. SAP97 is expressed in heart, lung, epithelial cells and brain. SAP97 may have a role in septate junction formation, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Diseases associated with DLG1 include Mayer-Rokitansky-Kuster-Hauser Syndrome and Depression.
Description
Our Anti-SAP97 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.
Short Description
Our Anti-SAP97 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K64/15. It is KO validated, detects human, mouse, and rat SAP97, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, IP, ELISA.
Synonyms
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene Name
Dlg1 Dlgh1
UniProt
Q62696
Host
Mouse
Reactivity
Human, Mouse, and Rat
Immunogen
Fusion protein amino acids 1-104 (N-terminus) of rat SAP97 (accession number Q62696) produced recombinantly in E. Coli
Target
SAP97
Clonality
Monoclonal
Isotype
IgG1
Clone
K64/15
Type
Primary Antibody
Applications
WB, IHC, ICC, IP, ELISA
Field of Research
Scaffold Proteins
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4
Molecular Weight
130 kDa
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
No cross-reactivity against PSD-95, Chapsyn-110 and SAP102 expressed in transfected cells
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Rat
WB Brain Quality Control
1
Conjugate
Unconjugated
RRID
AB_2091921

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