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Antitrypanosomal agent 19

CAT: 0804-HY-163003Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-163003Size:1 Each
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Description
Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT) -induced acute infectious toxicity in mice[1].
CAS Number
9007-83-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitrypanosomal-agent-19.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C([N+]([O-])=O)S1)NC/C=C/C(NC)=O
Molecular Formula
C10H11N3O4S
Molecular Weight
269.28
References & Citations
[1]Ajayi O et al. Discovery of an orally active nitrothiophene-based antitrypanosomal agent[J]. European Journal of Medicinal Chemistry, 2023: 115954.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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