Antitrypanosomal agent 8

Antitrypanosomal agent 8

• CAS Number: 9007-83-4
• UNSPSC Description: Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM)[1].
• Target Antigen: Parasite
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/antitrypanosomal-agent-8.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC1=CC=C(C(C)=O)C=C1)CSC2=NN=C(C3=CC=NC=C3)N2C4=CC=CC=C4
• Molecular Weight: 429.49
• References & Citations: [1]Shaykoon MS, et al. Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives. Bioorg Chem. 2020 Jul;100:103933.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported