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Antitrypanosomal agent 8

CAT: 0804-HY-147933Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-147933Size:1 Each
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Description
Antitrypanosomal agent 8 (compound 3b) has potent antitrypanosomal activity against Trypanosoma brucei with an IC50 value of 0.79 μM and exhibits certain cytotoxicity in L6 cells (IC50=80.95 μM) [1].
CAS Number
332376-42-8
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitrypanosomal-agent-8.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(C(C)=O)C=C1)CSC2=NN=C(C3=CC=NC=C3)N2C4=CC=CC=C4
Molecular Formula
C23H19N5O2S
Molecular Weight
429.49
References & Citations
[1]Shaykoon MS, et al. Design, synthesis and antitrypanosomal activity of heteroaryl-based 1,2,4-triazole and 1,3,4-oxadiazole derivatives. Bioorg Chem. 2020 Jul;100:103933.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Trypanosoma

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