Antitrypanosomal agent 13

CAT: 0804-HY-149986Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-149986Size:1 Each
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Description
Antitrypanosomal agent 13 (compound 4b) is a potent antitrypanosomal agent. Antitrypanosomal agent 13 has trypanocidal and cytotoxic activity with GI50 values of 0.18 and 8.4 μM for T. brucei and HL-60, respectively[1].
CAS Number
[9007-83-4]
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitrypanosomal-agent-13.html
Solubility
10 mM in DMSO
Smiles
CC[C@H]([C@@H]1[C@@H](C)C[C@@H](C)[C@@]2(CC[C@H](NC(NCCCC)=S)[C@@]3(O[C@@]([C@@H]4O[C@@H](C)[C@@](O)(CC)CC4)(C)CC3)O2)O1)C([C@H]([C@@H](O)[C@H](C)[C@]5([H])O[C@@H]([C@H](C(O[Na])=O)CC)CC[C@@H]5C)C)=O
Molecular Formula
C47H81N2NaO10S
Molecular Weight
889.21
References & Citations
[1]Antoszczak M, et, al. Synthesis of urea and thiourea derivatives of C20-epi-aminosalinomycin and their activity against Trypanosoma brucei. Eur J Med Chem. 2023 Mar 15;250:115241.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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