BChE-IN-26

CAT: 0804-HY-161156Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-161156Size:1 Each

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Description

BChE-IN-26 (Compound 7b) is a selective AChE and BChE inhibitor with Ki value of 35 μM and 1.6 μM. BChE-IN-26 has cytotoxicity to human neuroblastoma (SH-SY5Y) cell line. BChE-IN-26 can be used for the research of Alzheimer’s disease[1].

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/bche-in-26.html

Solubility

10 mM in DMSO

Smiles

ClC1=C(CN2CCN(CC3=C(Cl)C=CC=C3)CC2C(NO)=O)C=CC=C1

Molecular Formula

C19H21Cl2N3O2

Molecular Weight

394.29

References & Citations

[1]Soliman AM, et al. Piperazine-2-carboxylic acid derivatives as MTDLs anti-Alzheimer agents: Anticholinesterase activity, mechanistic aspect, and molecular modeling studies. Bioorg Chem. 2024 Jan;142:106916.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; BChE

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BChE-IN-26

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