TBAJ-5307

CAT: 0804-HY-161135Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-161135Size:1 Each
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Description
TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo[1].
CAS Number
[2332831-92-0]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tbaj-5307.html
Solubility
10 mM in DMSO
Smiles
BrC1=CC2=C(N=C(OC)C([C@@H](C3=CC=NC(OC)=C3OC)[C@](O)(C4=CC(OC)=NC(OC)=C4)CCN(C)C)=C2)C=C1
Molecular Formula
C30H35BrN4O6
Molecular Weight
627.53
References & Citations
[1]Ragunathan P, et, al. High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against non-tuberculous mycobacteria in vitro and in vivo. J Biol Chem. 2024 Jan 2:105618.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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