TBAP-001

CAT: 0804-HY-136567-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-136567-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay[1].
CAS Number
[1777832-90-2]
UNSPSC
12352005
Target
Raf
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tbap-001.html
Concentration
10mM
Purity
99.81
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=CC(F)=C2)NC3=CC=C(OC4=C(N=C5)C(NC5=O)=NC=C4)C=C3F
Molecular Formula
C27H23F2N7O3
Molecular Weight
531.51
References & Citations
[1]Caroline Joy, et al. 1 - (5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL) -3-[2-FLUORO-4-[ (3-OXO-4H-PYRIDO[2
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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