TBAP-001

• UNSPSC Description:

  TBAP-001 (Synthesis 13), extracted from patent WO2015075483A1, is a pan-RAF kinase inhibitor, with an IC50 of 62 nM in BRAF V600E kinase assay[1].

• Target Antigen:

  Raf

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tbap-001.html

• Smiles:

  O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=CC(F)=C2)NC3=CC=C(OC4=C(N=C5)C(NC5=O)=NC=C4)C=C3F

• Molecular Weight:

  531.51

• References & Citations:

  [1]Caroline Joy, et al. 1 -(5-TERT-BUTYL-2-ARYL-PYRAZOL-3-YL)-3-[2-FLUORO-4-[(3-OXO-4H-PYRIDO[2,

• Shipping Conditions:

  Room Temperature

• CAS Number:

  1777832-90-2