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TBA-354 (Standard)

CAT: 0804-HY-12485RSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12485RSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Polyphyllin VI (Standard) is the analytical standard of Polyphyllin VI. This product is intended for research and analytical applications. Polyphyllin VI, an active saponin, possess anti-cancer activities. Polyphyllin VI induces G2/M cell cycle arrest and triggers apoptosis. Polyphyllin VI induces caspase-1-mediated pyroptosis via the induction of ROS/NF-κB/NLRP3/GSDMD signal axis in non-small cell lung cancer[1][2][3].
CAS Number
1257426-19-9
UNSPSC
12352005
Target
Antibiotic; Bacterial; Reference Standards
Related Pathways
Anti-infection; Others
Field of Research
Infection
Smiles
FC(F)(F)OC1=CC=C(C2=CC=C(CO[C@H]3CN4C(OC3)=NC([N+]([O-])=O)=C4)C=N2)C=C1
Molecular Formula
C19H15F3N4O5
Molecular Weight
436.34
References & Citations
[1]Upton AM, et al. In Vitro and In Vivo Activities of the Nitroimidazole TBA-354 against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2015 Jan;59 (1) :136-44.|[2]Tasneen R, et al. Contribution of the Nitroimidazoles PA-824 and TBA-354 to the Activity of Novel Regimens in Murine Models of Tuberculosis. Antimicrob Agents Chemother. 2015 Jan;59 (1) :129-35.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

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MBS3601059-01TBA-354
A15431-100TBA-354 100mg
A15431-25TBA-354 25mg
A15431-50TBA-354 50mg
A15431-5TBA-354 5mg
A15431-10TBA-354 10mg
A15431-200TBA-354 200mg
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