4'-Ethynyl-2'-deoxycytidine

• UNSPSC Description:

  4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside. 4'-Ethynyl-2'-deoxycytidine can used in study acute lymphoblastic leukemia and diffuse large B-cell lymphoma[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/4-ethynyl-2-deoxycytidine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N=C1N=C(O)N([C@@H]2O[C@@](CO)(C#C)[C@@H](O)C2)C=C1

• Molecular Weight:

  251.24

• References & Citations:

  [1]Calbert ML, et al. 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress. Mol Cancer Ther. 2023 Dec 8.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  232588-95-3