4'-Ethynyl-2'-deoxycytidine

4'-Ethynyl-2'-deoxycytidine

• CAS Number: 232588-95-3
• UNSPSC Description: 4'-Ethynyl-2'-deoxycytidine is an anticancer nucleoside. 4'-Ethynyl-2'-deoxycytidine can used in study acute lymphoblastic leukemia and diffuse large B-cell lymphoma[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/4-ethynyl-2-deoxycytidine.html
• Solubility: 10 mM in DMSO
• Smiles: N=C1N=C(O)N([C@@H]2O[C@@](CO)(C#C)[C@@H](O)C2)C=C1
• Molecular Weight: 251.24
• References & Citations: [1]Calbert ML, et al. 4'-Ethynyl-2'-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress. Mol Cancer Ther. 2023 Dec 8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported