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4'-Ethynyl-2'-deoxyadenosine

CAT: 0931-T10141-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T10141-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
306305-07-7
Target
HIV Protease, Reverse Transcriptase, Others
Related Pathways
Microbiology/Virology, Others, Proteases/Proteasome
Bioactivity
4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, demonstrates potent activity against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity.
Smiles
NC1=C2C(N(C=N2)[C@@H]3O[C@](C#C)(CO)[C@@H](O)C3)=NC=N1
Molecular Formula
C12H13N5O3
Molecular Weight
275.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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