2'-Deoxycytidine

• UNSPSC Description:

  2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer[1][2].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/2_acute_-Deoxycytidine.html

• Purity:

  99.95

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

• Smiles:

  O=C1N([C@H]2C[C@H](O)[C@@H](CO)O2)C=CC(N)=N1

• Molecular Weight:

  227.22

• References & Citations:

  [1]Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81.|[2]Iwazaki A, et al. Intravenously administered 2'-deoxycytidine suppresses mouse myeloma tumor growth. Biol Pharm Bull. 2012;35(2):251-5.Clin Epigenetics. 2020 Feb 11;12(1):25.|Int J Biol Macromol. 2023 May 26;125063.|Nature. 2024 Dec 18.|Research Square Preprint. 2021 May.|Cell Rep. 2020 May 12;31(6):107640.|JCI Insight. 2022 Oct 13;e159419.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  Launched

• CAS Number:

  951-77-9