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EGFR-IN-93

CAT: 0804-HY-161031Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161031Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR-IN-93 (compound 18) is an allosteric inhibitor of T790M/L858R double mutant EGFR. EGFR-IN-93 can be used for non-small lung cancer (NSCLC) research[1].
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-in-93.html
Solubility
10 mM in DMSO
Smiles
[O-][N+](C1=CC(NC(C2=C(C)NC3=C2C=CC=C3)C4=C(F)C=CC(O)=C4)=CC=C1)=O
Molecular Formula
C22H18FN3O3
Molecular Weight
391.40
References & Citations
[1]Foschi F, et al. Structure-activity exploration of a small-molecule allosteric inhibitor of T790M/L858R double mutant EGFR. J Enzyme Inhib Med Chem. 2023 Dec;38 (1) :239-245.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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