IM-93

• Description:

  IM-93 inhibits ferroptosis and NETosis with an IC50 of 0.45 µM for cell death inhibition[1].

• UNSPSC:

  12352005

• Target:

  Ferroptosis

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/im-93.html

• Purity:

  99.00

• Solubility:

  DMSO : 20 mg/mL (ultrasonic; warming)

• Smiles:

  O=C(C(NCCCN(C)C)=C1C2=CN(C)C3=C2C=CC=C3)N(C(C)C)C1=O

• Molecular Formula:

  C21H28N4O2

• Molecular Weight:

  368.47

• References & Citations:

  [1]Dodo K, et al. Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis. ACS Med Chem Lett. 2019;10 (9) :1272-1278. Published 2019 Jul 30.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1173657-73-2]