KN-93

CAT: 0026-2524-1000Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-2524-1000Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cell-permeable. KN-93 is a potent inhibitor of Ca²⁺/calmodulin-dependent kinase type II (CaM kinase II) (IC₅₀ = 0.37 μM). It does not affect the activities of PKA, PKC, MLCK, or Ca2+-phosphodiesterase. Also a direct extracellular open channel blocker of voltage-gated potassium channels (IC₅₀ = 307 nM for Kv1.5). More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes.
Shipping Conditions
Gel pack
Storage Conditions
-20°C
Shelf Life
24 months

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