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HSD17B13-IN-93

CAT: 0804-HY-162219Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162219Size:1 Each
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Description
HSD17B13-IN-93 (Compound 9) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value for estradiol that is greater than 0.1 μM and less than or equal to 0.5 μM. HSD17B13-IN-93 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI) [1].
CAS Number
2848620-87-9
UNSPSC
12352005
Target
17β-HSD
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hsd17b13-in-93.html
Solubility
10 mM in DMSO
Smiles
FC1=C(O)C(Cl)=CC(C(NC2=C(C(NCC3=CC=CC=C3C(F)(F)F)=O)SC=N2)=O)=C1
Molecular Formula
C19H12ClF4N3O3S
Molecular Weight
473.83
References & Citations
[1]Anandan S K, et al. Dichlorophenol HSD17B13 inhibitors and uses thereof. U.S., WO2022103960. 2023-11-28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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