Nampt activator-4
CAT:
804-HY-157421
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Nampt activator-4
- CAS Number: 2847156-05-0
- UNSPSC Description: Nampt activator-4 is a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of 0.058 μM. Nampt activator-4 can enhance the nicotinamide adenine dinucleotide (NAD+) in cells[1].
- Target Antigen: NAMPT
- Type: Reference compound
- Related Pathways: Metabolic Enzyme/Protease
- Applications: Metabolism-sugar/lipid metabolism
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/nampt-activator-4.html
- Solubility: 10 mM in DMSO
- Smiles: O=C([C@@H]1CN(CCN1)C2=NC=NC3=NN(C=C32)C4=CC=C(C=C4)C(F)(F)F)NCC5=CC=C6SC=CC6=C5
- Molecular Weight: 537.56
- References & Citations: [1]Shen, Zhengnan et al. Synthesis, Optimization, and Structure-Activity Relationships of Nicotinamide Phosphoribosyltransferase (NAMPT) Positive Allosteric Modulators (N-PAMs). Journal of medicinal chemistry vol. 66,24 (2023): 16704-16727.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported