Nampt activator-3

• Target:

  NAMPT|||Others

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  NAMPT Activator-3, a derivative of NAT, is a potent activator of NAMPT, demonstrating an EC50 of 2.6 ?M and KD of 132 nM. It effectively shields cultured cells against toxicity induced by FK866 and has demonstrated significant neuroprotective effects in a chemotherapy-induced peripheral neuropathy (CIPN) mouse model, without any apparent toxicity [1].

• Smiles:

  O (CC (NC1=CC=C (O) C=C1) =O) C2=C (C (C) (C) C) C=CC=C2C#N

• Molecular Formula:

  C19H20N2O3

• Molecular Weight:

  324.37

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2790481-63-7