NAMPT activator-6

• Target :

  NAMPT

• Related Pathways :

  Metabolism

• Bioactivity :

  NAMPT activator-6, a regulatory molecule for the optical control system of NAMPT and NAD+, can be used to design efficient photoswitchable proteolysis-targeting chimeras (PS-PROTACs) for light-dependent, reversible regulation of NAMPT and NAD+, thereby reducing toxicity associated with inhibitor-based PS-PROTACs. This enables antitumor activity and in vivo modulation of NAMPT and NAD+ through optical manipulation [1].

• Smiles :

  S(=O)(=O)(C1=CC=C(NC(NCC=2C=CN=CC2)=O)C=C1)N3CCNCC3

• Molecular Formula :

  C17H21N5O3S

• Molecular Weight :

  375.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2237267-86-4