Nampt-IN-15

• UNSPSC Description:

  Nampt-IN-15 (Example 3) is an Nampt inhibitor. Nampt-IN-15 shows cytotoxicity against BxPC-3, HepG2, L540cy and MOLM-13, with IC50s of 38.5 nM, 8 nM, 8.5 nM, 7 nM respectively[1].

• Target Antigen:

  NAMPT

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nampt-in-15.html

• Purity:

  99.49

• Solubility:

  DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C(C1=CC(N)=CC=C1)N2CCC(CC2)CCCCNC(/C=C/C3=CN=CC=C3)=O

• Molecular Weight:

  406.52

• References & Citations:

  [1]Christopher Scott NEUMANN, et al. Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors. Patent. WO2018075600

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  2222981-61-3