c-Met-IN-21

c-Met-IN-21

• CAS Number: 3025958-01-1
• UNSPSC Description: c-Met-IN-21 (compound 54) is a c-met inhibitor with an IC50 value of 0.45 nM, and shows anti-tumor efficacy in vivo[1].
• Target Antigen: c-Met/HGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-met-in-21.html
• Solubility: 10 mM in DMSO
• Smiles: FC(F)(C1=NN=C2C=CC(C(C=C3CC4)=CC=C3N(CC(N5CCN(C(C)C)CC5)=O)C4=O)=NN12)C6=CC=C7C(C=CC=N7)=C6
• Molecular Weight: 610.66
• References & Citations: [1]Min W, et al. Discovery of potent and selective c-Met inhibitors for MET-amplified hepatocellular carcinoma treatment. Eur J Med Chem. Published online December 5, 2023.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported