c-Met-IN-13

c-Met-IN-13

• CAS Number: 2377724-93-9
• UNSPSC Description: c-Met-IN-13 is a potent c-Met inhibitor with an IC50 value of 2.43 nM. c-Met-IN-13 shows excellent cytotoxicity for cancer cells. c-Met-IN-13 shows antiproliferative activity in a concentration- and time- dependent manner. c-Met-IN-13 has the potential for the research of cancer[1].
• Target Antigen: c-Met/HGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-met-in-13.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(OC(C(C)(C)C)C(NC1=CC=C(OC2=CC=NC3=CC(OC)=C(OC)C=C23)C(F)=C1)=O)C4=CC=C(F)C=C4
• Molecular Weight: 550.55
• References & Citations: [1]Nan X, et al. Structure-based discovery of novel 4-(2-fluorophenoxy)quinoline derivatives as c-Met inhibitors using isocyanide-involved multicomponent reactions. Eur J Med Chem. 2020 May 1;193:112241.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported