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C-Met-IN-9

CAT: 0804-HY-115937Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-115937Size:1 Each
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Description
C-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1].
CAS Number
2760326-29-0
UNSPSC
12352005
Target
Apoptosis; c-Met/HGFR
Type
Reference compound
Related Pathways
Apoptosis; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-met-in-9.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN(C2=CC=C(F)C=C2)C=N1)NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=C4)C(F)=C3
Molecular Formula
C25H19F2N5O3
Molecular Weight
475.45
References & Citations
[1]Ju Liu, et al. Novel 4-phenoxypyridine derivatives bearing imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide moieties: Design, synthesis and biological evaluation as potent antitumor agents. Bioorg Chem. 2022 Jan 19;120:105629.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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