c-Met-IN-9

c-Met-IN-9

• CAS Number: 2760326-29-0
• UNSPSC Description: c-Met-IN-9, a 4-phenoxypyridine derivative, is a c-Met kinas inhibitor with an IC50 of 12 nM. c-Met-IN-9 induces cells apoptosis, and has antitumor activities[1].
• Target Antigen: Apoptosis; c-Met/HGFR
• Type: Reference compound
• Related Pathways: Apoptosis;Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-met-in-9.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CN(C2=CC=C(F)C=C2)C=N1)NC3=CC=C(OC4=CC(NC(C5CC5)=O)=NC=C4)C(F)=C3
• Molecular Weight: 475.45
• References & Citations: [1]Ju Liu, et al. Novel 4-phenoxypyridine derivatives bearing imidazole-4-carboxamide and 1,2,4-triazole-3-carboxamide moieties: Design, synthesis and biological evaluation as potent antitumor agents. Bioorg Chem. 2022 Jan 19;120:105629.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported