c-Met-IN-17
CAT:
804-HY-153831
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
c-Met-IN-17
- UNSPSC Description: c-Met-IN-17 is a potent c-Met kinase inhibitor with an IC50 of 0.031 μM. c-Met-IN-17 can be used in anticancer research.[1]. c-Met-IN-17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Target Antigen: c-Met/HGFR
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/c-met-in-17.html
- Solubility: 10 mM in DMSO
- Smiles: FC1=CC2=C(C(C3=CN(C(NC3=O)=O)C(C4=CC=CC=C4)C)=C1)NN=C2C#C
- Molecular Weight: 374.37
- References & Citations: [1]Michaelides IN, et al. Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor. J Med Chem. 2023 Jul 13;66(13):8782-8807.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported