c-Met-IN-17

c-Met-IN-17

• UNSPSC Description: c-Met-IN-17 is a potent c-Met kinase inhibitor with an IC50 of 0.031 μM. c-Met-IN-17 can be used in anticancer research.[1]. c-Met-IN-17 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
• Target Antigen: c-Met/HGFR
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/c-met-in-17.html
• Solubility: 10 mM in DMSO
• Smiles: FC1=CC2=C(C(C3=CN(C(NC3=O)=O)C(C4=CC=CC=C4)C)=C1)NN=C2C#C
• Molecular Weight: 374.37
• References & Citations: [1]Michaelides IN, et al. Discovery and Optimization of the First ATP Competitive Type-III c-MET Inhibitor. J Med Chem. 2023 Jul 13;66(13):8782-8807.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported