AChE-IN-47

CAT: 0804-HY-157296Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-157296Size:1 Each
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Description
AChE-IN-47 (compound g17) is a AChE inhibitor with the IC50 of 0.24 μM. AChE-IN-47 inhibits amyloid β peptides self-aggregation. AChE-IN-47 displays neuroprotective effects and effectively suppresses the intracellular accumulation of reactive oxygen species[1].
CAS Number
[3033056-55-9]
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-47.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C2C(N3CCCC3=NC2=C1)=O)CNS(=O)(C4=CC=CC=C4C(F)(F)F)=O
Molecular Formula
C20H17F3N4O4S
Molecular Weight
466.43
References & Citations
[1]Dong S, et al. Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease. Eur J Med Chem. 2024;264:116013.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE

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