HDAC1 Degrader-1

HDAC1 Degrader-1

• UNSPSC Description: HDAC1 Degrader-1 (compound 1a) is an HDAC1 degrader with anticancer activity. HDAC1 Degrader-1 significantly reduces HDAC1 levels in MM.1S multiple myeloma cells[1].
• Target Antigen: HDAC
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/hdac1-degrader-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCCCCCCC(NO)=O)C1=CC=C(NC(CC2(C3)C[C@@H](C4)C[C@H]3C[C@@H]4C2)=O)C=C1
• Molecular Weight: 455.59
• References & Citations: [1]Feller F et al. Targeted Protein Degradation of Histone Deacetylases by Hydrophobically Tagged Inhibitors[J]. ACS Medicinal Chemistry Letters, 2023.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported