HDAC6 degrader-4

• UNSPSC Description:

  HDAC6 degrader-4 is a PROTAC and a selective HDAC6 degrader consists of a non-selective HDAC inhibitor and thalidomide-type E3 ligase ligand. HDAC6 degrader-4 can be used for cancer research[1].

• Target Antigen:

  HDAC; PROTACs

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics;PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hdac6-degrader-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NO)CCCCCCC(N/N=C/C1=CC=C(OCCOCCOCCN2N=NC(CNC3=CC=CC(C(N4C(CC5)C(NC5=O)=O)=O)=C3C4=O)=C2)C=C1)=O

• Molecular Weight:

  775.81

• References & Citations:

  [1]Yang K, et al. Development of the first small molecule histone deacetylase 6 (HDAC6) degraders. Bioorg Med Chem Lett. 2018 Aug 1;28(14):2493-2497.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2235382-05-3