XSJ2-46

• Description :

  XSJ2-46, 5'-amino NI analog, is an antiviral agent. XSJ2-46 has anti-Zika virus activity. XSJ2-46 exhibits reasonable inhibition of RNA-dependent RNA polymerases (RdRp) with an IC50 value of 8.78 μM[1].

• CAS Number :

  [2265911-12-2]

• UNSPSC :

  12352005

• Target :

  Influenza Virus

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/xsj2-46.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@H]1[C@@H](O)[C@H](N2C3=C(N=C2)C(NCC4=CC(Cl)=CC=C4)=NC=N3)O[C@@H]1CNCC5=CC=C(C(F)(F)F)C=C5

• Molecular Formula :

  C25H24ClF3N6O3

• Molecular Weight :

  548.94

• References & Citations :

  [1]Chen X, et al. Investigation of novel 5'-amino adenosine derivatives with potential anti-Zika virus activity. Eur J Med Chem. 2023 Oct 1;261:115852.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported