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EGFR-IN-46

CAT: 0931-T63431-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63431-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2764772-88-3
Target
Apoptosis, FAK, EGFR, Others
Related Pathways
JAK/STAT signaling, Cytoskeletal Signaling, Others, Apoptosis, Tyrosine Kinase/Adaptors, Angiogenesis
Bioactivity
EGFR-IN-46 is a potent dual inhibitor of EGFR (IC50: 20.17 nM) and FAK (IC50: 14.25 nM) that significantly inhibits cancer cell growth and induces apoptosis.
Smiles
O(CCCNC1CCN(C)CC1)C=2C3=C(N=C(C2)C4=CC=C(C(F)(F)F)C=C4)C=C(OC)C(OC)=C3
Molecular Formula
C27H32F3N3O3
Molecular Weight
503.56
Shipping Conditions
Ice Packs
Storage Temperature
-20°C