BWX 46

• UNSPSC Description:

  BWX 46 (((Cys31, Nva 34)-Neuropeptide Y (27-36))2) is a selective Y5 receptor agonist with an IC50 value of 0.85 nM. BWX 46 can inhibit the synthesis of cAMP in Y5 cells[1].

• Target Antigen:

  Neuropeptide Y Receptor

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bwx-46.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1)=CC=C1C[C@H](N)C(N[C@]([C@@H](C)CC)([H])C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CSSC[C@@H](C(N[C@]([C@H](O)C)([H])C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC2=CC=C(O)C=C2)=O)=O)=O)=O)=O)NC([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@@]([C@@H](C)CC)([H])NC([C@@H](N)CC3=CC=C(O)C=C3)=O)=O)=O)=O)C(N[C@]([C@H](O)C)([H])C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC4=CC=C(O)C=C4)=O)=O)=O)=O)=O)=O)=O)=O)=O

• Molecular Weight:

  2597.07

• References & Citations:

  [1]Balasubramaniam A, et al. Bis(31/31')[[Cys(31), Nva(34)]NPY(27-36)-NH(2)]: a neuropeptide Y (NPY) Y(5) receptor selective agonist with a latent stimulatory effect on food intake in rats. Peptides. 2002;23(8):1485-1490.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  172997-92-1