MDM2/XIAP-IN-3

MDM2/XIAP-IN-3

• CAS Number: 2925583-17-9
• UNSPSC Description: MDM2/XIAP-IN-3 (compound 3e) is a dual MDM2/XIAP inhibitor. MDM2/XIAP-IN-3 reduces MDM2 and XIAP protein levels and increases p53 expression, thereby inhibiting cancer cell growth and causing cell death[1].
• Target Antigen: IAP; MDM-2/p53
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mdm2-xiap-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=S(C1=CC2=C(NC(C3=CC=C(C(C(C)C)=O)C=C3)C4C2OCC4)C=C1)(NC5=CC=CC(C(C)=O)=C5)=O
• Molecular Weight: 518.62
• References & Citations: [1]Albadari N, et al. Synthesis and biological evaluation of dual MDM2/XIAP inhibitors based on the tetrahydroquinoline scaffold. Eur J Med Chem. 2023 Jul 5;255:115423.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported