PROTAC MDM2 Degrader-3

PROTAC MDM2 Degrader-3

• CAS Number: 2249750-23-8
• UNSPSC Description: PROTAC MDM2 Degrader-3 is a MDM2 degrader based on PROTAC technology. PROTAC MDM2 Degrader-3 composes of a potent MDM2 inhibitor, linker, and the MDM2 ligand for E3 ubiquitin ligase[1].
• Target Antigen: E1/E2/E3 Enzyme; MDM-2/p53; PROTACs
• Type: Reference compound
• Related Pathways: Apoptosis;Metabolic Enzyme/Protease;PROTAC
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-mdm2-degrader-3.html
• Purity: 96.06
• Solubility: DMSO : 10 mg/mL (ultrasonic)
• Smiles: O=C(N1CC(N(CC(OCCOCCOCCOCCOC(CN2C(CN(C(N3[C@H](C4=CC=C(Cl)C=C4)[C@H](C5=CC=C(Cl)C=C5)N=C3C6=C(C=C(OC)C=C6)OC(C)C)=O)CC2)=O)=O)=O)CC1)=O)N7[C@H](C8=CC=C(Cl)C=C8)[C@H](C9=CC=C(Cl)C=C9)N=C7C%10=C(C=C(OC)C=C%10)OC(C)C
• Molecular Weight: 1437.25
• References & Citations: [1]Method of inducing of self-degradation of MDM2 using E3 ubiquitin ligase dimer amide small molecule PROTACs. CN108610333A.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported