XIAP BIR2/BIR2-3 inhibitor-2

XIAP BIR2/BIR2-3 inhibitor-2

• CAS Number: 1609384-83-9
• UNSPSC Description: XIAP BIR2/BIR2-3 inhibitor-2 is a dual inhibitor of BIR2 and BIR2-3 with IC 50s less than 1 nM. XIAP BIR2/BIR2-3 inhibitor-2 can used in study cancers[1].
• Target Antigen: IAP
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/xiap-bir2-bir2-3-inhibitor-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@@](C(N[C@H](C(N[C@H](C2=NN=NN2)CC3=CC=C(OCC4=CN5N=N4)C=C3)=O)CC6=CC(C=CC=C7)=C7C=C6)=O)([H])[C@](CC1)([H])N8C=C(COC9=CC=C(C[C@H](NC([C@@H](NC([C@]%10([H])[C@@]5([H])CCN%10C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)=O)CC%11=CC(C=CC=C%12)=C%12C=C%11)=O)C(O)=O)C=C9)N=N8)[C@H](C(C)(C)C)NC([C@H](C)NC)=O
• Molecular Weight: 1529.75
• References & Citations: [1]Robert M. Borzilleri, et al. Macrocyclic compounds for inhibition of inhibitors of apoptosis. US20150284427A1. 2015-10-08.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported