Products for Research Use Only
RegisterLogin

MDM2/4-p53-IN-3

CAT: 0804-HY-151171Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-151171Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MDM2/4-p53-IN-3 is a MDM2/4-p53 protein-protein interactions (PPIs) inhibitor (IC50s: 18.5 nM for MDM2-p53, 14.8 nM for MDM4-p53) . MDM2/4-p53-IN-3 can be used in the research of cancers, such as colon cancer[1].
UNSPSC
12352005
Target
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mdm2-4-p53-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C([C@@H]1C2=CC=CC(Cl)=C2F)=NN(C3CCCCC3)[C@@]41C(NC5=C4C=CC(Cl)=C5)=O)OCC
Molecular Formula
C25H24Cl2FN3O3
Molecular Weight
504.38
References & Citations
[1]Margarida Espadinha, et al. Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors. Eur J Med Chem. 2022 Aug 5;241:114637.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W340313-01P53-MDM2-IN-4
HY-121893-01P53-MDM2-IN-3
HY-151170MDM2/4-p53-IN-2
HY-151169MDM2/4-p53-IN-1
HY-163661P53-MDM2-IN-5
HY-W340839-01P53-MDM2-IN-1
HY-161039MDM2-p53-IN-18
HY-161041MDM2-p53-IN-20
HY-162927P53-MDM2-IN-6
HY-116052-01P53-MDM2-IN-2

Alternative Products

CatalogName
MBS5816859MDM2/4-p53-IN-3
GTR19185216-01Rel-MDM2/4-p53-IN-3
GTR19220800-01MDM2/4-p53-IN-2
T67698-01P53-Mdm2 inhibitor 4
MBS5806416rel-MDM2/4-p53-IN-2
TBI1350-25MGNutlin-3, p53/mdm2 inhibitor
BA3476-10p53-MDM2-IN-1
BA3473-5MDM2-p53-IN-16
T86876-01MDM2-p53-IN-18
GTR19261866-01P53-MDM2-IN-2

Popular Products