XIAP BIR2/BIR2-3 inhibitor-1

XIAP BIR2/BIR2-3 inhibitor-1

• CAS Number: 1609384-59-9
• UNSPSC Description: XIAP BIR2/BIR2-3 inhibitor-1 (compound 3) is a dual inhibitor of BIR2 and BIR2-3 with IC50s of 1.9 and 0.8 nM, respectively. XIAP BIR2/BIR2-3 inhibitor-1 can used in study cancers[1].
• Target Antigen: IAP
• Type: Reference compound
• Related Pathways: Apoptosis
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/xiap-bir2-bir2-3-inhibitor-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@@](C(N[C@H](C(N[C@H](CCCN2C=C(CO[C@@](CCN3C([C@H](C(C)(C)C)NC([C@H](C)NC)=O)=O)([H])[C@@]3([H])C4=O)N=N2)C(O)=O)=O)CC5=CC(C=CC=C6)=C6C=C5)=O)([H])[C@@](OCC7=CN(CCC[C@@H](NC([C@@H](N4)CC8=CC(C=CC=C9)=C9C=C8)=O)C(O)=O)N=N7)([H])CC1)[C@H](C(C)(C)C)NC([C@H](C)NC)=O
• Molecular Weight: 1409.63
• References & Citations: [1]Robert M. Borzilleri, et al. Macrocyclic compounds for inhibition of inhibitors of apoptosis. WO2014074665A1. 2014-05-15.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported