CSF1R-IN-17
CAT:
804-HY-155550
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
CSF1R-IN-17
- UNSPSC Description: CSF1R-IN-17 (compound 9) is a potent and selective CSF1R antagonist, with an IC50 of 0.2 nM. CSF1R-IN-17 can inhibit osteoclast differentiation[1].
- Target Antigen: c-Fms
- Type: Reference compound
- Related Pathways: Protein Tyrosine Kinase/RTK
- Applications: COVID-19-immunoregulation
- Field of Research: Inflammation/Immunology
- Assay Protocol: https://www.medchemexpress.com/csf1r-in-17.html
- Solubility: 10 mM in DMSO
- Smiles: OCCC1=CC=C(C2=NC3=C(N(C)CC4CCOCC4)N=CN=C3N2)C=C1
- Molecular Weight: 367.44
- References & Citations: [1]Aarhus TI, et, al. A highly selective purine-based inhibitor of CSF1R potently inhibits osteoclast differentiation. Eur J Med Chem. 2023 Jul 5;255:115344.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported