CSF1R-IN-6

• UNSPSC Description:

  CSF1R-IN-6 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-6 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-6 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 5)[1].

• Target Antigen:

  c-Fms

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/csf1r-in-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN=C(C)N(C)C1=O)NC2=NC=C(C=C2)OC3=NC=NC(C4=CN(C)N=C4)=C3

• Molecular Weight:

  418.41

• References & Citations:

  [1]Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2716184-87-9