CSF1R-IN-6

CSF1R-IN-6

• CAS Number: 2716184-87-9
• UNSPSC Description: CSF1R-IN-6 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-6 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-6 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 5)[1].
• Target Antigen: c-Fms
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/csf1r-in-6.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CN=C(C)N(C)C1=O)NC2=NC=C(C=C2)OC3=NC=NC(C4=CN(C)N=C4)=C3
• Molecular Weight: 418.41
• References & Citations: [1]Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported