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CSF1R-IN-6

CAT: 0804-HY-144042Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-144042Size:1 Each
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Description
CSF1R-IN-6 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-6 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-6 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 5) [1].
CAS Number
2716184-87-9
UNSPSC
12352005
Target
C-Fms
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/csf1r-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CN=C(C)N(C)C1=O)NC2=NC=C(C=C2)OC3=NC=NC(C4=CN(C)N=C4)=C3
Molecular Formula
C20H18N8O3
Molecular Weight
418.41
References & Citations
[1]Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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