CSF1R-IN-5

CSF1R-IN-5

• CAS Number: 2716184-93-7
• UNSPSC Description: CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-5 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-5 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 11)[1].
• Target Antigen: c-Fms
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/csf1r-in-5.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CN=C2N(CCC2)C1=O)NC3=NC=C(C=C3)OC4=CC=NC(C5=CN(C)N=C5)=C4
• Molecular Weight: 429.43
• References & Citations: [1] Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported