CSF1R-IN-5

• CAS Number:

  2716184-93-7

• UNSPSC Description:

  CSF1R-IN-5 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-5 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-5 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 11)[1].

• Target Antigen:

  c-Fms

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/csf1r-in-5.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=CN=C2N(CCC2)C1=O)NC3=NC=C(C=C3)OC4=CC=NC(C5=CN(C)N=C5)=C4

• Molecular Weight:

  429.43

• References & Citations:

  [1] Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported