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CSF1R-IN-4

CAT:
804-HY-144040
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
CSF1R-IN-4 - image 1

CSF1R-IN-4

  • CAS Number: 2716185-86-1
  • UNSPSC Description: CSF1R-IN-4 is a potent inhibitor of CSF1R. CSF-1R is expressed in macrophages, and the survival and differentiation of macrophages depends on the CSF-1/CSF-1R signaling pathway. CSF1R-IN-4 affects the exchange of inflammatory factors between TAMs and glioma cells. CSF1R-IN-4 has the potential for the research of cancer disease (extracted from patent WO2021197276A1, compound 104)[1].
  • Target Antigen: c-Fms
  • Type: Reference compound
  • Related Pathways: Protein Tyrosine Kinase/RTK
  • Applications: Cancer-programmed cell death
  • Field of Research: Cancer
  • Assay Protocol: https://www.medchemexpress.com/csf1r-in-4.html
  • Solubility: 10 mM in DMSO
  • Smiles: O=C(C1=CC=CN(C2CC2)C1=O)NC3=NC=C(OC4=CC(C5=CN(C)N=C5)=NC=C4)C=C3
  • Molecular Weight: 428.44
  • References & Citations: [1]Wei-Guo Su, et al. Amide compounds and uses thereof. Patent WO2021197276A1.
  • Shipping Conditions: Room temperature
  • Clinical Information: No Development Reported