AChE-IN-45

• Description :

  AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor with IC50 of 11.57±0.45 nM that shows antioxidant and neuroprotective activities[1].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ache-in-45.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(NC1=NC=CN=C1)CSC(N2C3=CC=C(S(=O)(N)=O)C=C3)=NC4=C(C=C(I)C=C4)C2=O

• Molecular Formula :

  C20H15IN6O4S2

• Molecular Weight :

  594.41

• References & Citations :

  [1]Aiten M Soliman, et al. Novel iodoquinazolinones bearing sulfonamide moiety as potential antioxidants and neuroprotectors. Sci Rep. 2023 Sep 20;13 (1) :15546.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported