α-Amylase/α-Glucosidase-IN-8

α-Amylase/α-Glucosidase-IN-8

• UNSPSC Description: α-Amylase/α-Glucosidase-IN-8 (Compound 7p) is a potent dual inhibitor of α-amylase and α-glucosidase, with IC50s of 10.19 and 10.33 μM, respectively. α-Amylase/α-Glucosidase-IN-8 has good anti-oxidant activity(IC50 = 14.93 μM). α-Amylase/α-Glucosidase-IN-8 can be used for the research of diabetes[1].
• Target Antigen: Amylases; Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-amylase-α-glucosidase-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N(CC1=CC=CC([N+]([O-])=O)=C1)C/2=O)SC2=C/C3=CC=C(O)C(OCC)=C3
• Molecular Weight: 400.41
• References & Citations: [1]Singh G, et al. 3,5-Disubstituted-thiazolidine-2,4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation. Eur J Med Chem. 2024 Jan 12;266:116139.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported