MAT2A-IN-11

CAT: 0804-HY-155148Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155148Size:1 Each
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Description
MAT2A Allosteric inhibitor 1 (compound 5) is a MAT2A selective inhibitor of methionine adenosyltransferase (MAT) with an IC50 of 6.8 nM[1].
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mat2a-in-11.html
Solubility
10 mM in DMSO
Smiles
CCN1N=C2C(C=CC(NC(C3=CC(C4CC4)=NC5=C3C=NN5CC)=O)=C2)=C1
Molecular Formula
C21H22N6O
Molecular Weight
374.44
References & Citations
[1]Kalliokoski T, et al. Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg Med Chem Lett. 2023 Oct 1;94:129450..
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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