MAT2A-IN-11

MAT2A-IN-11

• UNSPSC Description: MAT2A Allosteric inhibitor 1 (compound 5) is a MAT2A selective inhibitor of methionine adenosyltransferase (MAT) with an IC50 of 6.8 nM[1].
• Target Antigen: Methionine Adenosyltransferase (MAT)
• Type: Reference compound
• Related Pathways: Epigenetics;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/mat2a-in-11.html
• Solubility: 10 mM in DMSO
• Smiles: CCN1N=C2C(C=CC(NC(C3=CC(C4CC4)=NC5=C3C=NN5CC)=O)=C2)=C1
• Molecular Weight: 374.44
• References & Citations: [1]Kalliokoski T, et al. Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening. Bioorg Med Chem Lett. 2023 Oct 1;94:129450..
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported