MAT2A-IN-20

• Description:

  MAT2A-IN-20 (Compound A49) is an inhibitor for methionine adenosyltransferase 2A (MAT2A) with an IC50 ≤50 nM. MAT2A-IN-20 inhibits human UGT1A1 with an IC50 of 28.45 μM. MAT2A-IN-20 exhibits antitumor in mouse models[1].

• UNSPSC:

  12352005

• Target:

  Methionine Adenosyltransferase (MAT)

• Related Pathways:

  Epigenetics; Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  O=C1C (C2=CC3=C (N=C (C (C) (C) O) N3C) C=C2) =NC4=C (N1C5=CC=C (C=C5) OC (F) F) N=C (OCC) N=C4

• Molecular Formula:

  C26H24F2N6O4

• Molecular Weight:

  522.50

• References & Citations:

  [1]Wang K, et al., Pyrimido nitrogen-containing six-membered aromatic heterocyclic compound and application thereof. CN115504980A.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  3018834-98-2