MAT2A-IN-2

• UNSPSC Description:

  MAT2A-IN-2 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-2 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2020243376A1, compound 172)[1].

• Target Antigen:

  Somatostatin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mat2a-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C(C2=CN3C=CN=C3C=C2)=CC4=C(N1C5=CC=C(C=C5)OC)N=C(NCC(F)(F)F)N=C4

• Molecular Weight:

  466.42

• References & Citations:

  [1]Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2020243376A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2565671-21-6