MAT2A-IN-2

MAT2A-IN-2

• CAS Number: 2565671-21-6
• UNSPSC Description: MAT2A-IN-2 is a potent inhibitor of MAT2A. The expression level of MAT2A is abnormally high in several types of tumors, including gastric, colon, liver and pancreatic cancers. MAT2A-IN-2 reduces the proliferative activity of MTAP-deficient cancer cells. MAT2A-IN-2 has the potential for the research of cancer diseases (extracted from patent WO2020243376A1, compound 172)[1].
• Target Antigen: Somatostatin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mat2a-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C1C(C2=CN3C=CN=C3C=C2)=CC4=C(N1C5=CC=C(C=C5)OC)N=C(NCC(F)(F)F)N=C4
• Molecular Weight: 466.42
• References & Citations: [1]Zenon D. Konteatis, et al. Heterobicyclic inhibitors of mat2a and methods of use for treating cancer. Patent WO2020243376A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported