MAT2A-IN-10
CAT:
804-HY-149915
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No

MAT2A-IN-10
- CAS Number: 2924825-23-8
- UNSPSC Description: MAT2A-IN-10 (Compound 28) is an orally active MAT2A inhibitor with an IC50 of 26 nM. MAT2A-IN-10 can be used for the research of cancer[1].
- Target Antigen: Methionine Adenosyltransferase (MAT)
- Type: Reference compound
- Related Pathways: Epigenetics;Metabolic Enzyme/Protease
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/mat2a-in-10.html
- Solubility: 10 mM in DMSO
- Smiles: CCOC1=NC2=C(C(N(C(N2C3=CC=C(C=C3)OC(F)F)=O)C4=CC=C5N=C6CN(CCN6C5=C4)C)=O)C=C1
- Molecular Weight: 534.51
- References & Citations: [1]Zhang S, et al. Design and Structural Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High In Vivo Potency and Oral Bioavailability. J Med Chem. 2023 Apr 13;66(7):4849-4867.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported