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Antitrypanosomal agent 14

CAT: 0804-HY-155025Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155025Size:1 Each
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Description
Antitrypanosomal agent 14 (Compound 1) is a T. brucei inhibitor (EC50: 0.47 μM) . Antitrypanosomal agent 14 inhibits TbGSK3 with an IC50 of 12 μM. Antitrypanosomal agent 14 can be used for the research of Human African trypanosomiasis[1].
CAS Number
1447933-37-0
UNSPSC
12352005
Target
GSK-3; Parasite
Type
Reference compound
Related Pathways
Anti-infection; PI3K/Akt/mTOR; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitrypanosomal-agent-14.html
Solubility
10 mM in DMSO
Smiles
CC(C)(C)C(C1=C(N)N=C(NC2CCCCC2)S1)=O
Molecular Formula
C14H23N3OS
Molecular Weight
281.42
References & Citations
[1]Cleghorn LAT, et al. Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. J Med Chem. 2023 Jul 13;66 (13) :8896-8916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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