Antitrypanosomal agent 14
CAT:
804-HY-155025
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Antitrypanosomal agent 14
- CAS Number: 9007-83-4
- UNSPSC Description: Antitrypanosomal agent 14 (Compound 1) is a T. brucei inhibitor (EC50: 0.47 μM). Antitrypanosomal agent 14 inhibits TbGSK3 with an IC50 of 12 μM. Antitrypanosomal agent 14 can be used for the research of Human African trypanosomiasis[1].
- Target Antigen: GSK-3; Parasite
- Type: Reference compound
- Related Pathways: Anti-infection;PI3K/Akt/mTOR;Stem Cell/Wnt
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/antitrypanosomal-agent-14.html
- Solubility: 10 mM in DMSO
- Smiles: CC(C)(C)C(C1=C(N)N=C(NC2CCCCC2)S1)=O
- Molecular Weight: 281.42
- References & Citations: [1]Cleghorn LAT, et al. Development of a 2,4-Diaminothiazole Series for the Treatment of Human African Trypanosomiasis Highlights the Importance of Static-Cidal Screening of Analogues. J Med Chem. 2023 Jul 13;66(13):8896-8916.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported